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  • Systemic Lupus Erythematosus

  • Fibromyalgia

  • Multiple Sclerosis

  • Psoriasis

  • Crohn's Disease

  • Irritable Bowel Disease

  • Type 1 Diabetes

  • Ankylosing Spondylitis

  • Polymyalgia Rheumatica

  • Rheumatoid Arthritis

  • Sj√∂gren's syndrome

  • Thyroiditis, Hashimotos

BACKGROUND:

Stromal vascular fraction (SVF) represents an attractive source of adult stem cells and progenitors, holding great promise for numerous cell therapy approaches. In 2017, it was reported that 1524 patients received autologous SVF following the enzymatic digestion of liposuction fat. To date, almost 10,000 patients have been treated with SVF. The treatment was safe and effective and patients showed significant clinical improvement. In a collaborative study, we analyzed SVF obtained from 58 patients having degenerative, inflammatory, autoimmune diseases, and advanced stage cancer.

CONCLUSIONS:

We found that a 2:1 ratio of ADSCs to HSC-progenitors seems to be the key for a successful cell therapy. These findings open the way to future rational design of new treatment regimens for individuals by adjusting the cell ratio before the treatment.