In search of the Holy Grail of Healing - Part 2

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Mesenchymal stem cells are fabulous mono-nuclear cells found in all tissues of the body.  they are found in abundance in the stroma of adipose tissue that I touch on in Part 1.  In my research on stem cells I came upon a realization.  Much like chicken soup, if we focus only on the chicken and study it's contents.   I'm sure we would be discouraged with it's inability to reduce the symptoms of a cold/flu when isolated from the broth.  But when the broth is combined with the chicken, we get a whole new clinical outcome.  So it is with the stem cell, by itself it is very cool with amazing properties, but without it's broth it is less effective in a clinical setting.  Within the broth of the stroma lives an even smaller subset of vesicles that have illuded scientists for years.  I can remember clearly being taught that these extracellular vesicles (EV's) were the garbage trucks that transported garbage and debrit out of the cell.  Boy, they were WAY wrong.  These EV's are the communication system of the cells.  The EV's are critical for gene expression and behavior of stem cells and all other cells in the body.  They may communicate with a cell right next door, or it may communicate with a cell on the opposite end of the body.

EV's in recent years have almost stole center stage away from the stem cell as it turns out, the reason stem cells are so wonderful, may not be entirely because they are so awesome, but becuase they secrete awesomeness in the form of EV's.

In fact, when EV's are isolated, which is quite difficult to do by the way as they are very tiny bubbles, many many microns smaller than a cell.  They have the same abilities to change behavior and gene expression in cells as the stem cells.  You can effectively remove the stem cell altogether and just release the EV's in concentrated form and create the same effect, at leased in vitro.  

It's an exciting field that is just ramping up, clinical trials are just getting underway for therapeutic use.  I read an article recently posted, one of the Green bay Packers new players from the Seattle Seahawks (can't believe they let him go!) - Jimmy Graham, just returned from a cell therapy program in the UK utilizing just EV's, no direct injections into his ailing knee, simply an iv of EV's and apparently in his own words is "feeling great".  He remarked after the therapy he had watched a movie and afterwords he stood up and felt no knee pain at all which was not the case just prior.  Over a year has gone by and he's still pain free.  Time will tell if it's only the anti-inflammatory effect or some kind of true healing that took place.  But I know I'm a believer, it just makes sence when you study it.

In search of the Holy Grail of Healing - Part 1

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It has been my lifelong journey to find the fountain of youth.  I've spent the last 25+ years exploring natural healing and regeneration.  I came up wanting every time.  Spent thousands of hours, thousands of dollars exploring and researching trending stories, tropical berries, rare earth gases, ionizing waters, vitamin regimens, spinal manipulative techniques, chi activation, functional medicine, meditation and the list goes on.  The pursuit has always been to activate and or release the innate regenerative properties of the body, similar to a time when it was not ever a thought.  You know, like you did when you were twelve.  The ability to heal with great enthusiasm fades as we age, and it's heart breaking.  Just as we transition to a time when we have more time, the so called "golden years" we seem to be instead of ramping up our exploration of this world we are besieged by an onslaught of debilitating illnesses, aches, pains, moans and groans.  

How is it that along our path our bodies decided, without consultation by the way, to fall into a state of not only disrepair but into the lion's den of medical miss-information in the guise of science.  Science, as I have learned is malleable, plastic, persuasive and even deceitful when in the hands of financial concerns of shareholders.  Why is it that you go to the doctors with a belly ache and multiple vials of blood, a CT and Ultrasound and $2,000 later you're told there's nothing wrong with you and you have a stomach virus, instructed to go home and take the medications, rest and everything will be fine - "Thanks for doing business with us!" is what they should say, because that's what you did, you did business with them.

Every century or so a discovery is found that changes everything.  We see a "paradigm shift".  Something is discovered that changes everything, it refocuses the entire science and medical community in a new direction.  This is occurring as I write this letter.  Just think "biotech", how's the biotech industry?  It's BOOM city.  Billions are flowing into the new biology of healing with the re-discovery of cell biology and innate healing.  The science of regenerative medicine is exploding and heading to your town despite the criticism of old hard-liners who do not want anything to change because they are very comfortable doing things just the way things always have been done.  

Change is uncomfortable and requires learning, study and re-tooling.  Those who re-tool and learn what the cell biologists are bringing to light are the early pioneers in regenerative medicine.  Specifically I'm talking about cell therapy.  But more precisely, stromal vascular fraction (SVF).   It is the SVF that is the stuff of legends, teaming with stem cells, progenitor cells, growth factors, cytokines, exosomes, etc.  This stroma is of natural origin, it comes from you within the adipose tissue.  Yes, I mean your fat!  As it turns out your fat is absolutely an amazing organ - and yes it's considered an organ by many biologists.  Strangely enough, it was really the frequent discovery by plastic surgeons that fat is an amazing substance to work with. The fat tissues throughout your body has some amazing properties.  I wont bore you with the details however, feel free to research SVF on you own on the PubMed website, research is no longer the privilege of the educated but is available to anyone willing to put in the time.

The physician's office today producing SVF from the tissues of the patient are wielding an amazing regenerative tool in the fight against damaged, dying and decaying tissues in the body.  It can be deployed (injected) into damaged tissues, it can be deployed intravenously for systemic disease conditions, auto-immune conditions, traumatic brain injury and on and on.  In the near future you will not be given a pill, you'll be deploying your cells.  But here's the kicker.  It's going to be kept out of the hands of your local mainstream medical clinics and hospitals.  Why, if it's so great?  Because, if you think about it, these are YOUR cells.  Not a medication, not a synthetic chemical, not titanium hardware, not another million dollar body scanner.  Can you begin to see why this new paradigm is going to struggle to get to the surface?  Billions are being poured into research by big pharma to find a cell therapy that can be synthesized, bottled and given a lengthy expiration date to be put on the shelf for sale.  Sorry, but you can't synthesize the bodies innate healing powers, it's not reproducible.  It can only be deployed appropriately.  Not to be duplicated.

It's an exciting time to be a pioneer in the field of regenerative medicine and I'm having the best time of my life exploring what is possible.  I see the difference it makes in the lives of those we serve.  I cheer the scientists and biologists who continue to advance this field in the face of heavy criticism of big pharma's influence throughout the medical community and mass media who have billions upon billions at stake.  

Heart Patients can breathe a sigh of relief

The stem cells and other progenitor cells concentrated as SVF or Stromal Vascular Fraction from the patients fat after a mini-liposuction has the potential to radically alter the way patients are treated following a heart attack, stroke, angina, or heart failure.  Other attempts at stem cell therapy have also shown to be beneficial as well.  But the greatest concentration of these regenerative cells and stem cells are found in the fat derived stromal vascular fraction. 

Experts say initial findings suggest those who have suffered crippling heart failure can go on to lead normal lives.

Dr John Hung, a cardiology specialist working on the trials in Edinburgh, said that because anyone can have the treatment it has the potential to save huge numbers of lives and at the same time slash the NHS bill for the future care of heart failure patients.

He added: “We think about one in five people who survive a major heart attack are likely to benefit from the therapy, and this could mean hundreds of thousands in the UK or many millions across the world.

"There should also be healthcare savings from the reduced costs for medication, ongoing treatment and recurrent hospitalisations.”

One patient who was given a 50-50 chance of surviving five years after suffering a major heart attack, because of the damage it caused, has spoken of his gratitude of being given the radical treatment.

One patient called Bill, not his real name, now has almost normal heart function and he believes he has been given a second chance at life.

We are now offering this life saving therapy in our Seattle and Salt Lake locations.  Contact us soon to see what we can do for you or a loved one.

Tarek El Moussa, reality show real estate mogul gets out stem cell procedure done for his lower back pain.

We have performed dozens of spine related stem cell procedures over the last couple years.  Having been involved with spine care over the last 20+ I can say I feel more confident than ever dealing with complicated spinal conditions then ever before.  And more and more celebrities are taking notice.

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if you are suffering with spine related problems please connect with me and let's talk it over.

There'sa lot to be optimistic about. 

Regards... 

Stem Cells - only a small portion of the magic

It's is the unfortunate philosophical bent of most scientists to have a reductionist mindset.  That is to narrow their vision down to the least common denominator of a substance looking for the one thing that makes something work.  Learning more and more about less and less until they know absolutely everything about nothing at all.  Not to disparage this practice as it does add to the body of knowledge. 

However, it is this myopic tunnel vision that is plaguing our research facilities.  This is also true of stem cell research.  So much effort goes into investigating the nature of the "stem cell" as the Holy Grail of regeneration.  But what of the other cells it communicates with?  What of the exosomes that it uses to transfer DNA and other proteins.  What of the extra cellular matrix and environment of the cell?

Let me introduce you to Stromal Vascular Fraction (SVF).  This is the end product after a simple mini-liposuction procedure and subsequent cell processing in a lab.  The SVF is the "soup" that is concentrated for the purpose of cellular regeneration.  It can be used for degenerated joints as well as a number of auto-immune, neuro and other degenerative conditions.  The "Healing Miracle" documentary that came out recently had a lot of good information as well regarding its clinical use.

At the same time, SVF is a bit of a taboo in arenas that are heavily influenced by big pharma.  Why?  Because there is absolutely not a dime to be made for these folks.  As such, they never turn down an opportunity to shun it's practice as we saw in a Consumer's Report article that was completely and factually untrue as expressed by scientist everywhere. So don't expect Eli Lilly to fund a double blind, placebo controlled, randomized crossover clinical trial to show all the benefits of this "all natural" organic product that can't be patented. 

The attached paper is a wonderful review of the nature of stromal vascular fraction (SVF) and the conditions it appears to be naturally reversing.  Enjoy

Stem Cell for Traumatic Brain Injury (TBI)

Once again we are seeing incredible progress with the iv administration of adipose (fat) derived stem cell on the recovery of brain injury, such as in stroke, trauma, lack of oxygen, or heart attack.  Most recently an 11 year old who suffered cardiac arrest after a freak accident involving a pellet gun that misfired and logged a pellet in his heart.

Although he survived the ordeal, he was left with considerable brain injury.  However, fortunately they were alerted to a stem cell facility outside the US that had the capability to extract stem cells from the boy's fat.  The cells are then culture expanded to create hundreds of millions of cells to then administer them through an iv.  

What most people are unaware is that this process can be performed here in the US.  In fact, here in Salt Lake City were are performing this very procedure.  The only difference is that we do not need to culture the cells.  In our proprietary cell processing, as performed in all Cell Surgical approved locations, we are able to not only concentrate the stem cells, but also the other related cells, cytokines, growth factors and adipocytes that are crucial to healing and repair.

We stand in bewilderment of the innate power of the body, it is only now that we are learning ways to work with it to optimize the regenerative powers of the body.  These are glorious times.

Non-Healing Ulcers and Stem Cells

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Fat derived stem cells are an increasing source of cells that have the ability to repair ulcerations from diabetes, radiation induced ulcers, bed sores, and poor circulation says a study published in the Stem Cell Research & Therapy

Treatment with stem cells might be a new treatment option for these patients. Stem cells have the potential to differentiate into numerous types of cells. Over the last decade, stem cell therapy has shown great potential in the treatment of a variety of different conditions, such as orthopedic disorders, inflammatory diseases, hepatic failure, and autoimmune disorders. At the time of writing, adverse events have not been reported; therefore, stem cell treatment is currently regarded as safe. A review including more than 1400 patients found a favorable safety profile of adipose-derived stem cells (ADSC), but also highlighted the poor quality of most studies in regard to registering adverse events.  Better safety data collection can be found at the Cell Surgical Network website in California.

Adipose tissue is an excellent source of autologous ADSC and can be harvested easily compared with bone marrow-derived stem cells (BMSC). Adipose tissue has in recent years surpassed bone marrow as the preferred source of mesenchymal stem cells. Besides being abundant, far easier to harvest, and with a lower risk of complications for the patient, adipose tissue additionally contains about 40 times more stem cells than bone marrow. A simple liposuction of the abdomen or inner thigh performed under local or general anesthesia is sufficient to harvest the required number of ADSC without any significant risk of complications. ADSC can be either freshly isolated or cultured. The culturing takes several days or weeks, and cannot be performed as a same-day procedure nor is culturing available inside the US.  Currently culturing ADSC's is not allowed in the US under federal regulations.  However, with the adipose collection and processing following the procedures outlined by the Cell Surgical Network, culturing may be unnecessary given the high yield of ADSC collected in these facilities across the nation.  For a complete list of facilities that offer this service click here

 

Exosomes - the future of promoting the paracrine effect.

Stem cells are unique cells with amazing healing capabilities, it's only been in the last decade that a substantial number of scientists are investigating and providing insights on how to use them most effectively with the help of clinicians having "boots on the ground" actually witnessing the effects and what they're capable of.  As well as what concurrent therapies or interventions might increase the stem cells ability to work their magic.

Here is were exosomes come in.  Science has recently discovered what actually happens when the endogenous stem cells are deployed in a body joint, or spine.  It appears that it's the presence of the stem cells that's most important, not the idea that they just repair damage but that they have a unique signaling system, the "paracrine effect".  This is the cell to cell communication that goes on once the stem cells are implanted.  One of the most important talking, or signalling messengers molecules are exosomes excreted from the stem cells to the surrounding cells and tissues encouraging them to repair and regenerate.  through a complicated process of angiogenesis (formation of new blood vessels) and tissue renewal they appear to be able to improve the promotion of the stem cells.

Although exosomes were discovered over five decades ago, interest among the scientific community didn’t pique until much later.  Specifically, in the last ten years, the number of annual publications about exosomes have almost increased by tenfold (from 1,570 published papers in 2007 to 14,000 in 2017).   

How to BOOST your own stem cell production

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I'm often asked, "What can I do nutritionally to increase my chances of success with my stem cell procedure?"  This has lead me down some interesting paths of research over the years and one technique continues to outshine the others, by a long shot.  And honestly, I've only had 2 patients take me up on it.  It is FASTING, in fact a 5 day water fast, ouch... I know you didn't want to hear it, nobody does.  Just the thought makes people cringe.  Knowing instantly that they can't conceive of that kind of self torture, and instantly decide - nope, not going to happen.

Here's the good part.  It's really not that hard, once you get passed  the first 48 hours the rest is a breeze, kinda.  It's still hard but the rewards are indisputable given all the research that surrounds this age old therapy.  Utilized over the ages by all the great physicians.  In fact, On October 3, 2016, the Nobel Prize in Physiology or Medicine was awarded to Yoshinori Ohsumi for “discoveries of the mechanisms for autophagy.”  The reason it works says Omer Yilmaz, an MIT professor of biology, a member of the Koch Institute for Integrative Cancer Research, is that fasting invokes all the restorative components of the body while eating up and destroying dead cells, dying cells and genetically damaged cells in a process called autophagy. Google it, or click the links above.

Even better.  There are much less dramatic ways to induce the same autophagy without the extreme 5 day water fast.  It's called intermittent fasting.  This is when you go several hours between meals, and the farther apart the meals the better.  An example, eating your last meal at 7pm and then skipping breakfast (no it's not the most important meal of the day) and waiting until early afternoon before your next meal, say at 2pm.  This creates a 5 hour eating window for you to get in the calories you need while invoking the autophagy principle in the prior 19 hours of fasting.  Sure, the autophagy works better the longer you go without food, but for those who just can't imagine going a whole day without something, or perhaps for other medical reasons such as not taking your meds on an empty stomach.  Then this method may be just what the doctor ordered.

Feel free to comment below.  Would love to hear your experiences.

 

Adult or youth stem cells best?

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A common question patients have when inquiring about stem cell therapy is whether or not their stem cells are still any good?  This is a very good question when your 78 years old and thinking your cells are too old to regenerate.  The industry standard is to use a common sense opinion and say well, yes... if your older then your stem cells are older and less viable, less enthusiastic, less capable.  But, a recently published paper in the Frontiers in Cardiovascular Medicine may change that opinion.  When cells are harvested from an elderly patient and then through an new process converted back to a pluripotent stem cell (iPSC), they appear to be as viable, as enthusiastic and capable as that of an embryo.  The reason we get older and heal slower, is not because our cells are weaker, it is because we simply don't have as many stem cells.  And that's exactly why we concentrate them in mass quantities for our therapy. That's amazing.

Dr Charles Nemeroff "You infuse these cells, and they literally go to the hot spots, your knee, your chest."

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Dr. Charles Nemeroff, Director of the University of Miami Center on Aging and Chairman of the Department of Psychiatry and Behavioral Sciences at University of Miami, Speaking about the use of mesenchymal stem cells intravenously administered.  As described in his interview with Psychiatric Times. He touched on a variety of subjects related to depression, in addition he lauded the benefits of intravenously administered stem cells as he has witnessed for patients.  Although it is not condoned by the FDA, FDA Chairman Dr Gottlieb has agreed to not interfere with offices that adhere to good, sterile procedures for the next 3 years at which time it is anticipated that this practice will be legally considered a "drug" therapy.  This would mean that the same rigorous rules applied to a new drug would also be applied to stem cell therapy.  However, given that drug companies can not patent this procedure (it's an all natural procedure), they really can't make any money here which means no money to pay for the rigorous and extremely expensive laboratory testing.  Being in the 100's of millions of dollars it is unlikely any local clinic will be funding it.  It will likely mean leaving the US in order to use your own cells to heal yourself.  It is no doubt the drug companies pressure on the FDA that will likely win in the courts.

We can't have people side stepping the pharmacy and healing themselves now can we, that would be horrible - insert huge sarcasm here.

Although stem cell therapy is still evolving, the next ten years are going to be exciting. With billionaires getting older, you watch... they're dumping their own money into biotech to find the fountain of youth.  Follow the link below:

So... it may not be the weight after all that's wrecking your knees?

Could the extra weight that most Americans are carrying around just be inconsequential to their knees wearing out prematurely?  Remembering, correlation does not imply causation.  Meaning, maybe the extra weight really has nothing to do with those bad knees?  The gut microbiome is once again suspect in another condition, osteoarthritis.  This isn't new, I've been reading about and experiencing this with daily patient interaction for years.  Your gut bacteria have a lot to say about your general inflammatory markers, or the degree at which your body maintains a constant low grade inflammatory condition.  The end result - osteoarthritis, atherosclerosis, autoimmune, degenerative joint disease, etc...

The solution - better diet, exercise, stay healthy, sleep... easy right?  Nope, in fact getting regular exercise, adequate sleep, a healthy diet and positive view of the future and life in general is one of the most challenging aspects of the human condition.  But you can do it!

Never underestimate the importance of motion palpation

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Over the years I have personally witnessed time and time again a misdiagnosis.  The classic case is the individual with said "hip pain" and diagnosed with degenerative osteoarthritis of the hip as seen on an x-ray/MRI and the recommendation of complete hip replacement.  I have learned to never take that diagnosis at face value.  More often than I can count, after a complete physical examination I find the real culprit to be the lower spine, facet damage, bursitis or one of the sacroiliac joints.  Yes, they may indeed have some degenerative OA of the hip but if that's not causing the pain, then what good is it to perform a total hip replacement only to observe the patient when the surgery is complete and the pain remains!

This phenomenon can easily be related to any other joint in the body as well.  I'm always shocked after the exam when a patient remarks, "Why didn't my doctor do that?" and I say, "Do what?" "You felt around and moved me around in different positions until you found my problem, my doctor never touched me." Wow, just wow.

 I don't understand the omission of the physical exam by many doctors.  Getting a second opinion is always a good idea when something like spine surgery or a total joint replacement is recommended.  And with the advancements of today, options like stem cell therapy is proving to be a major game changer and making the spine surgery/joint replacement folks very nervous.  Don't get me wrong, joint replacement surgery will never go away as there are times when it is completely necessary.  But, necessary is becoming less and less common.

Stem cell transplant 'game changer' for MS patients

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You may be familiar with "bone marrow transplant", it's been a regular practice in medicine since the 50's.  But did you know in reality this is a stem cell transplant?  In this article you'll hear of the amazing results they are getting with stem cell transplant.  What you may not know is that this is available in the U.S.  The only difference in our office is that we do not chemically destroy your immune system.  we instead simply infuse your stem cells intravenously every 3 months over the course of the year up to two years.  In this way we are able to avoid the very dangerous practice of decimating your immune system with chemotherapy drugs, while still giving your stem cells an opportunity to "reset" your immune system.  The idea is to "reset" or "reboot" your immune system so as to stop attacking your nervous system which is the cause of the symptoms associated with MS.

Are all stem cell clinics the same?

With the explosion of stem cell clinics across the globe over the last few years, combined with limited resources from regulatory agencies both foreign and domestic. How do you know if you're dealing with the real deal?

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it is completely possible to start a stem cell clinic doing everything right from the start and do excellent work and help people tremendously. It is also possible to cut corners, use known bogus amniotic fluid or placental stem cells to make a quick buck, fill the coffers full of gold until word gets out, then off to the next unassuming town.  It's happening all around the country making a bad name for those who are using sound science behind their operation.  It's very inexpensive to get a bogus clinic up and running, it's VERY expensive to get a legitimate clinic up and running. Physicians aren't cheap, the tools of the trade aren't cheap.  The guided imaging tools aren't cheap.   So, there's one good clue. Do they have 200k+ invested in imaging? Look around, take a tour of the office and observe, if it looks really expensive it usually is. Do they have a 100k+ invested in their in-office lab?  Just ask to see their lab. Do they have a physician\medical officer? If they have these 3 things their is a good chance they're doing things right and you can be optimistic about your results. Of course with any medical practice there's little substitution for experience. Do they have lots of happy patients that refer to that office? For more information or need some helpful guidance feel free to contact me. I'm very passionate about this work and want to see it protected from corruption. 

www.mystemcellusa.com

MS sufferers get renewed hope with stem cells

Several trials continue to show real results with MS. And not just temporary relief but actual cure. It would be fantastic to see this as the approved treatment for MS as well as several other autoimmune conditions such as Lupus, Psoriasis, Rheumatoid arthritis, etc.

Follow the link for more information on the most recent study from Time magazine.  

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No Tamaflu? No Problem - why take a drug when you've got...

Tamaflu

Move over...

take Tamaflu and you could get...

  • nausea,
  • vomiting,
  • diarrhea,
  • dizziness,
  • headache,
  • nosebleed,
  • eye redness or discomfort,
  • sleep problems (insomnia), or
  • cough or other respiratory problems.

These and other negative side effects are possible when taking this prescription drug.  A whole lot better idea is to take Quercetin.  

As described by Byron J. Richards, Board Certified Clinical Nutritionist.  Quercetin is as effective without the side effects!  Wow, did you know that?

And further, Dr Mercola also goes into great depth in explaining the benefits of Quercetin here.

So, the next time you hear on the local news there's a shortage of Tamaflu, just remember that is designed intentionally to rally the troops to demand more Tamaflu!  The Feds and State health departments will get pressure from well meaning citizens to demand that we be prepared for next flu season by spending your tax dollars in the 100's of millions to stockpile Tamaflu!  Save the war-cry and just get Quercetin.