Non-Healing Ulcers and Stem Cells

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Fat derived stem cells are an increasing source of cells that have the ability to repair ulcerations from diabetes, radiation induced ulcers, bed sores, and poor circulation says a study published in the Stem Cell Research & Therapy

Treatment with stem cells might be a new treatment option for these patients. Stem cells have the potential to differentiate into numerous types of cells. Over the last decade, stem cell therapy has shown great potential in the treatment of a variety of different conditions, such as orthopedic disorders, inflammatory diseases, hepatic failure, and autoimmune disorders. At the time of writing, adverse events have not been reported; therefore, stem cell treatment is currently regarded as safe. A review including more than 1400 patients found a favorable safety profile of adipose-derived stem cells (ADSC), but also highlighted the poor quality of most studies in regard to registering adverse events.  Better safety data collection can be found at the Cell Surgical Network website in California.

Adipose tissue is an excellent source of autologous ADSC and can be harvested easily compared with bone marrow-derived stem cells (BMSC). Adipose tissue has in recent years surpassed bone marrow as the preferred source of mesenchymal stem cells. Besides being abundant, far easier to harvest, and with a lower risk of complications for the patient, adipose tissue additionally contains about 40 times more stem cells than bone marrow. A simple liposuction of the abdomen or inner thigh performed under local or general anesthesia is sufficient to harvest the required number of ADSC without any significant risk of complications. ADSC can be either freshly isolated or cultured. The culturing takes several days or weeks, and cannot be performed as a same-day procedure nor is culturing available inside the US.  Currently culturing ADSC's is not allowed in the US under federal regulations.  However, with the adipose collection and processing following the procedures outlined by the Cell Surgical Network, culturing may be unnecessary given the high yield of ADSC collected in these facilities across the nation.  For a complete list of facilities that offer this service click here