It's is the unfortunate philosophical bent of most scientists to have a reductionist mindset. That is to narrow their vision down to the least common denominator of a substance looking for the one thing that makes something work. Learning more and more about less and less until they know absolutely everything about nothing at all. Not to disparage this practice as it does add to the body of knowledge.
However, it is this myopic tunnel vision that is plaguing our research facilities. This is also true of stem cell research. So much effort goes into investigating the nature of the "stem cell" as the Holy Grail of regeneration. But what of the other cells it communicates with? What of the exosomes that it uses to transfer DNA and other proteins. What of the extra cellular matrix and environment of the cell?
Let me introduce you to Stromal Vascular Fraction (SVF). This is the end product after a simple mini-liposuction procedure and subsequent cell processing in a lab. The SVF is the "soup" that is concentrated for the purpose of cellular regeneration. It can be used for degenerated joints as well as a number of auto-immune, neuro and other degenerative conditions. The "Healing Miracle" documentary that came out recently had a lot of good information as well regarding its clinical use.
At the same time, SVF is a bit of a taboo in arenas that are heavily influenced by big pharma. Why? Because there is absolutely not a dime to be made for these folks. As such, they never turn down an opportunity to shun it's practice as we saw in a Consumer's Report article that was completely and factually untrue as expressed by scientist everywhere. So don't expect Eli Lilly to fund a double blind, placebo controlled, randomized crossover clinical trial to show all the benefits of this "all natural" organic product that can't be patented.
The attached paper is a wonderful review of the nature of stromal vascular fraction (SVF) and the conditions it appears to be naturally reversing. Enjoy